Argentina scored seven tries as Steve Tandy’s first game in charge of Wales ended in a comprehensive loss.
The 52-28 victory gave Los Pumas their highest score and largest winning margin against the Dragons.
Four of Argentina’s tries came in a first half when they led 14-0, were pegged back to 14-14, but still turned round in command at 31-14.
This was Wales’ 10th successive home defeat. Their cause was not helped by yellow cards for backs Ben Thomas and Tomos Williams.
Wales only ended a record run of 18 successive Test defeats with a 31-22 win over Japan in Kobe in July.
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Their loyal fans must have feared the worst when Argentina surged into a 14-0 lead with just 11 minutes played.
The Pumas’ driving maul paved the way for prop forward Pedro Delgado’s seventh-minute try, his first for Argentina.
Argentina are coming in strong!
Delgado marks a memorable moment as he scores his first try for his country
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Los Pumas, who beat both the All Blacks and Wallabies in this year’s Rugby Championship, soon doubled their lead.
Wing Mateo Carreras kicked ahead and flyhalf Geronimo Prisciantelli won the race to touch down for his maiden Test try.
Wales hit back with two converted tries of their own.
Tom Rogers, scything through the midfield, was well supported by Wales captain Jac Morgan and the flanker’s excellent pass released scrumhalf Tomos Williams for a try between the posts.
Wales are on the scoreboard!
Breaking through the Argentinian midfield, Tom Rogers finds Morgan, whose wonderful offload delivers Williams to the try line
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Wales, roared on by a freshly-inspired crowd under the closed roof of the Millennium Stadium, were level minutes later.
Morgan was hauled down short of the line following a tap penalty but Williams’ superbly-timed pass allowed the onrushing Dewi Lake to power over. The conversion left the game all square.
Wales found themselves a man down when inside centre Thomas was sin-binned for lashing out with the boot at Argentina flanker Pablo Matera.
Los Pumas regained their composure and edged 17-14 in front through Santiago Carreras’ 31st-minute penalty.
Before Thomas’ yellow card expired, scrumhalf Simon Benitez Cruz dived against the post for a 38th-minute try.
From the kick-off, with the last play of the half, the Pumas scored again.
Matera beat several tacklers before producing a left-footed kick worthy of a flyhalf that was scooped up by dashing wing Mateo Carreras, who scrambled over the line.
Carreras maintained his perfect record from the kicking tee to put Argentina 17 points ahead at the break.
Just three minutes into the second half Prisciantelli and Bautista Delguy combined before the wing barged past Rogers.
To make matters worse for Wales, Williams was then shown a yellow card for tackling a man without the ball.
A cheer rang round the ground in the 45th minute as Louis Rees-Zammit came off the bench. It was the 24-year-old wing’s first Wales appearance since the 2023 World Cup after an unsuccessful 18-month stint in American football.
Morgan pulled a try back but Prisciantelli scored his second – Argentina’s sixth – in the 62nd minute, intercepting Thomas’ pass and racing clear from 25m out.
Gerónimo Prisciantelli striking the perfect moment to score his second try of the afternoon for Argentina against Wales in Cardiff
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Wales wing Blair Murray crossed the Pumas’ line seven minutes from time but Argentina had the last word through replacement loose forward Santiago Grondona’s 79th-minute try.
Photo: Michael Steele/Getty Images
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Gerónimo Prisciantelli striking the perfect moment to score his second try of the afternoon for Argentina against Wales in Cardiff